exRNAdisease

Entry Detail

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General Information

Database ID: exR0753511 RNA Name: AC007218.1 RNA Type: lncRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 9666885 End Site(bp): 9676843 External Links: ENSG00000260362

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADNP2 chr18 80109262 80147523 + ARHGDIA chr17 81867721 81871378 - ATXN3 chr14 92044496 92106621 - BASP1 chr5 17065598 17276843 + CCDC6 chr10 59788747 59906556 - CCT6A chr7 56051685 56063989 + CS chr12 56271699 56300391 - DYNLL2 chr17 58083419 58095542 + EIF4H chr7 74174245 74197101 + GTF3C3 chr2 196763035 196799725 - JMJD8 chr16 681670 684528 - MAPKAPK2 chr1 206684944 206734283 + NPM1 chr5 171387116 171411137 + PRRC2C chr1 171485551 171593511 + RPL32 chr3 12834485 12841582 - RPS29 chr14 49570984 49599164 - TCF7L2 chr10 112950247 113167678 + TM9SF4 chr20 32109714 32167258 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC003975.1 chr7 125917871 125933832 + AC078905.1 chr15 87038717 87047303 + LINC01356 chr1 112820170 112850643 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.