exRNAdisease

Entry Detail

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General Information

Database ID: exR0753540 RNA Name: AC008040.1 RNA Type: lncRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 169939353 End Site(bp): 169966734 External Links: ENSG00000239219

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CCNL1 chr3 157146508 157160760 - COG4 chr16 70480568 70523558 - DICER1 chr14 95086228 95158010 - EPHA4 chr2 221418027 221574202 - FHL1 chrX 136146702 136211359 + FOXRED2 chr22 36487190 36507101 - PABPC4 chr1 39560816 39576790 - RANGAP1 chr22 41245611 41286251 - SPG11 chr15 44562696 44663678 - TRIP6 chr7 100867387 100873454 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-214-3p chr1 172138816 172138837 - hsa-miR-124-3p chr8 64379210 64379231 + hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-506-3p chrX 147230753 147230773 - hsa-miR-761 chr1 51836375 51836396 - hsa-miR-4306 chr13 99643123 99643139 + hsa-miR-3619-5p chr22 46091059 46091080 + hsa-miR-4644 chr6 170330813 170330835 + hsa-miR-605-3p chr10 51299623 51299644 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC01783 chr1 16533886 16536172 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.