exRNAdisease

Entry Detail

General Information

Database ID:

exR0753545

RNA Name:

AC008105.3

RNA Type:

lncRNA

Chromosome:

chr17

Starnd:

-

Coordinate:

Start Site(bp):

45190931

End Site(bp):

45222222

External Links:

ENSG00000267121

Disease Information

Disease Name:	Glioblastoma Multiforme
Disease Category:	Cancers
MeSH ID:	D005909
Type:	Neoplasms/Neoplasms, Glandular and Epithelial
Alias:	Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID:	GSE106804
Description:	Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:	Cancer vs Control
Case Disease Type:	Glioblastoma Multiforme
Case Disease SubType:	NA
Case Sample:	Glioblastoma Multiforme
Control Sample:	Healthy
Number of Case:	13
Number of Control:	6
Number of Samples:	19

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AFF4	chr5	132875395	132963634	-
AL136454.1	chr1	192716132	192716653	+
CLN6	chr15	68206992	68257211	-
LRRC59	chr17	50375059	50397523	-
PHRF1	chr11	576470	612222	+
PTGES3	chr12	56663341	56688408	-
RPS15A	chr16	18781295	18790383	-
SMAD4	chr18	51028394	51085045	+
SPCS3	chr4	176319966	176332245	+
TAF6L	chr11	62771357	62787342	+
TUBB4B	chr9	137241287	137243707	+
WIPF1	chr2	174559572	174682916	-

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

NA

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	29330365
Title:	Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:	Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:	Nat Commun. 2018 Jan 12;9(1):175.
Description:	Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.