exRNAdisease

Entry Detail

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General Information

Database ID: exR0753604 RNA Name: AC010642.2 RNA Type: lncRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 58309727 End Site(bp): 58327248 External Links: ENSG00000283103

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF1 chr6 30571393 30597179 + CSTF1 chr20 56392371 56406362 + DPH1 chr17 2030110 2043430 + EDARADD chr1 236348257 236502915 + FAU chr11 65120630 65122177 - GNAS chr20 58839718 58911192 + HSP90AB1 chr6 44246166 44253888 + LAMB1 chr7 107923799 108003187 - LCLAT1 chr2 30447226 30644225 + MRPL37 chr1 54184041 54225464 + OVCA2 chr17 2042022 2043425 + PHB2 chr12 6965327 6970753 - RCAN3 chr1 24502351 24541040 + RPL15 chr3 23916545 23924374 + RPLP0 chr12 120196699 120201235 - RPS14 chr5 150442635 150449739 - TM6SF1 chr15 83107572 83144854 + ZDHHC17 chr12 76763588 76853696 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.