exRNAdisease

Entry Detail

General Information

Database ID:

exR0753675

RNA Name:

AC016831.1

RNA Type:

lncRNA

Chromosome:

chr7

Starnd:

-

Coordinate:

Start Site(bp):

130876809

End Site(bp):

130913310

External Links:

ENSG00000226380

Disease Information

Disease Name:	Glioblastoma Multiforme
Disease Category:	Cancers
MeSH ID:	D005909
Type:	Neoplasms/Neoplasms, Glandular and Epithelial
Alias:	Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID:	GSE106804
Description:	Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:	Cancer vs Control
Case Disease Type:	Glioblastoma Multiforme
Case Disease SubType:	NA
Case Sample:	Glioblastoma Multiforme
Control Sample:	Healthy
Number of Case:	13
Number of Control:	6
Number of Samples:	19

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
MIB1	chr18	21704957	21870957	+
MTRNR2L1	chr17	22523111	22524663	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-141-3p	chr12	6964155	6964176	+
hsa-miR-200a-3p	chr1	1167916	1167937	+
hsa-miR-522-3p	chr19	53751264	53751285	+
hsa-miR-493-3p	chr14	100869116	100869137	+
hsa-miR-296-3p	chr20	58817626	58817647	-
hsa-miR-224-3p	chrX	151958584	151958606	-

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
BX284668.2	chr1	16870945	16883659	+
LINC-PINT	chr7	130938963	131110176	-

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	29330365
Title:	Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:	Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:	Nat Commun. 2018 Jan 12;9(1):175.
Description:	Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.