exRNAdisease

Entry Detail

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General Information

Database ID: exR0753707 RNA Name: AC020928.2 RNA Type: lncRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 36773712 End Site(bp): 36775908 External Links: ENSG00000267353

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPL13 chr16 89560657 89566828 + QSOX2 chr9 136206333 136245812 - TMED9 chr5 177592203 177597242 + AC010422.3 chr19 12643831 12648397 - EFR3B chr2 25042076 25159135 + JUND chr19 18279694 18281622 - ATIC chr2 215311956 215349773 + RPL28 chr19 55385345 55403250 + PTBP1 chr19 797075 812327 + MYO9B chr19 17075781 17214537 + ALDH16A1 chr19 49453225 49471050 + YIPF2 chr19 10922185 10928681 - FLT4 chr5 180601506 180649624 - RPRD2 chr1 150363091 150476566 + PACS2 chr14 105300563 105398147 + MEAF6 chr1 37492575 37514774 - MTDH chr8 97644184 97730260 + IMP3 chr15 75639085 75648706 - RPL18 chr19 48615328 48619184 - PGBD5 chr1 230314490 230426332 - UBE2B chr5 134371469 134392108 + RAB12 chr18 8609437 8639382 + SLX1A chr16 30193887 30197561 + PPIL1 chr6 36854827 36874803 - B4GALT4 chr3 119211732 119240946 - ZNF730 chr19 23075210 23147221 + STYXL1 chr7 75996338 76048004 - DNMT3B chr20 32762385 32809356 + SEC61A1 chr3 128051641 128071683 + RPLP1 chr15 69452814 69456205 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-455-5p chr9 114209449 114209470 + hsa-miR-663a chr20 26208243 26208264 - hsa-miR-1908-5p chr11 61815209 61815229 - hsa-miR-3180-3p chr16 16309936 16309957 + hsa-miR-3150b-3p chr8 95072924 95072944 - hsa-miR-4784 chr2 131491208 131491227 - hsa-miR-6787-5p chr17 82236673 82236694 + hsa-miR-6816-5p chr22 20114726 20114746 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + SLX1A-SULT1A3 chr16 30193892 30204310 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.