exRNAdisease

Entry Detail

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General Information

Database ID: exR0753806 RNA Name: AC060780.1 RNA Type: lncRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 43148368 End Site(bp): 43171037 External Links: ENSG00000267002

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FLII chr17 18244815 18258738 - MTRNR2L1 chr17 22523111 22524663 + RPL8 chr8 144789765 144792587 - RARA chr17 40309180 40357643 + APOE chr19 44905791 44909393 + POTEG chr14 19402486 19434341 - TRIM28 chr19 58544064 58550722 + EHMT1 chr9 137618992 137870016 + BRCA1 chr17 43044295 43170245 - ARHGDIA chr17 81867721 81871378 - ACTG1 chr17 81509971 81523847 - P4HB chr17 81843161 81860624 - ZG16B chr16 2830169 2839585 + ELL2 chr5 95885098 95961851 - SLC43A2 chr17 1569267 1628886 - SRSF5 chr14 69726900 69772005 + ATP5MC1 chr17 48892765 48895871 + CENPA chr2 26764289 26801067 + SDHAF3 chr7 97117698 97181763 + PFN1 chr17 4945652 4949061 - PLXNB2 chr22 50274979 50307646 - ADRA2C chr4 3766348 3768526 + HMGCR chr5 75336329 75362101 + HCFC1 chrX 153947557 153971818 - VMP1 chr17 59707192 59842255 + ALDOC chr17 28573115 28576948 - RPLP1 chr15 69452814 69456205 + MARCKSL1 chr1 32333839 32336233 - TTC19 chr17 15999784 16045015 + SPINT2 chr19 38244035 38292615 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.