exRNAdisease

Entry Detail

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General Information

Database ID: exR0753854 RNA Name: AC078846.1 RNA Type: lncRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 129604548 End Site(bp): 129611630 External Links: ENSG00000273329

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AHI1 chr6 135283532 135497765 - CD44 chr11 35138870 35232402 + GAK chr4 849276 932373 - GTPBP2 chr6 43605316 43629264 - LARP1 chr5 154712843 154817605 + NUP155 chr5 37288137 37371106 - PAXIP1 chr7 154943687 155003124 - PIEZO1 chr16 88715338 88785220 - RACK1 chr5 181236897 181248096 - RAI1 chr17 17681458 17811453 + SRCAP chr16 30698209 30741409 + SREBF2 chr22 41833079 41907307 + UBE3C chr7 157138916 157269370 + ZC3H7B chr22 41301525 41360147 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-23a-3p chr19 13836595 13836615 - hsa-miR-23b-3p chr9 95085265 95085287 + hsa-miR-126-5p chr9 136670616 136670636 + hsa-miR-130a-5p chr11 57641212 57641233 + hsa-miR-23c chrX 20017101 20017122 - hsa-miR-4766-3p chr22 40813893 40813913 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.