exRNAdisease

Entry Detail

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General Information

Database ID: exR0753884 RNA Name: AC087190.3 RNA Type: lncRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 9104848 End Site(bp): 9113181 External Links: ENSG00000263244

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PLA2G12A chr4 109709989 109730070 - AC126283.2 chr4 109713916 109801999 - C16orf72 chr16 9091644 9121635 + RPS29 chr14 49570984 49599164 - AC018523.2 chr11 14493783 14520344 - STK4 chr20 44966479 45080021 + C3orf38 chr3 88149959 88168729 + PSMA1 chr11 14504874 14643635 - RPL9 chr4 39452521 39458949 - LRP6 chr12 12116025 12267044 - TXNRD1 chr12 104215779 104350307 + USP53 chr4 119212587 119295517 + ZNF19 chr16 71464555 71565089 - ANP32B chr9 97983341 98015943 + UNK chr17 75784806 75825799 + ACTB chr7 5527148 5563784 - PKD1 chr16 2088708 2135898 - RPS4X chrX 72255679 72277248 - PMF1 chr1 156212993 156240042 + SGSM2 chr17 2337498 2381058 + PCBP1 chr2 70087477 70089203 + EIF3G chr19 10115014 10119918 - NUDT5 chr10 12165330 12196144 - RAB11B chr19 8389981 8404434 + AC010547.4 chr16 71447600 71489311 - HNRNPA1 chr12 54280193 54287088 + ADGRE1 chr19 6887566 6940459 + HNRNPA0 chr5 137745651 137754363 - TOR1AIP2 chr1 179839967 179877803 - CNBP chr3 129169484 129183922 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-23b-5p chr9 95085227 95085248 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand Z92544.2 chr16 689001 692554 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.