exRNAdisease

Entry Detail

---



General Information

Database ID: exR0753939 RNA Name: AC092720.1 RNA Type: lncRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 87595131 End Site(bp): 87600337 External Links: ENSG00000260750

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CDK6 chr7 92604921 92836594 - CLSTN1 chr1 9728926 9823984 - CXXC4 chr4 104468308 104494901 - CYBA chr16 88643289 88651054 - F12 chr5 177402140 177409576 - FOXK2 chr17 82519713 82644662 + GDF11 chr12 55743122 55757264 + GK chrX 30653359 30731456 + HERPUD1 chr16 56932142 56944864 + IQSEC1 chr3 12897043 13283281 - ITM2B chr13 48232612 48270357 + IWS1 chr2 127436207 127526886 - JUNB chr19 12791486 12793315 + MIDN chr19 1248553 1259140 + MMS22L chr6 97142161 97283217 - PBXIP1 chr1 154944076 154956123 - RAPGEF2 chr4 159103013 159360174 + REEP2 chr5 138439057 138446969 + SRRM1 chr1 24631716 24673281 + TMEM185B chr2 120217479 120223400 - TWF1 chr12 43793723 43806375 - ZDHHC2 chr8 17156482 17224799 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL031005.1 chr1 21266082 21267251 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.