exRNAdisease

Entry Detail

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General Information

Database ID: exR0753974 RNA Name: AC097478.1 RNA Type: lncRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 89743792 End Site(bp): 89744305 External Links: ENSG00000274238

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTG1 chr17 81509971 81523847 - CCSER1 chr4 90127535 91601913 + CDC42SE2 chr5 131245493 131398447 + ENO1 chr1 8861000 8879190 - FOXM1 chr12 2857681 2877155 - GAPDH chr12 6534512 6538374 + GGPS1 chr1 235327350 235344532 + HMGB2 chr4 173331376 173334432 - HSP90AB1 chr6 44246166 44253888 + IGFBP2 chr2 216632828 216664436 + MCM6 chr2 135839626 135876443 - MRFAP1 chr4 6640091 6642745 + MT-CO2 chrMT 7586 8269 + MT-ND2 chrMT 4470 5511 + NREP chr5 111662621 111997464 - PCNA chr20 5114953 5126626 - PPFIA1 chr11 70270700 70385312 + PPM1B chr2 44167969 44244384 + RACK1 chr5 181236897 181248096 - RELA chr11 65653597 65663090 - RPL36A chrX 101390824 101396154 + RPL36A-HNRNPH2 chrX 101391011 101412297 + SERPINE2 chr2 223975045 224039318 - SIN3A chr15 75369379 75455842 - SLC1A5 chr19 46774883 46788594 - TBCE chr1 235328570 235448952 + TMEM258 chr11 61768501 61792802 - UQCRFS1 chr19 29205320 29213151 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand SNHG1 chr11 62851984 62855953 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.