exRNAdisease

Entry Detail

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General Information

Database ID: exR0754002 RNA Name: AC104257.1 RNA Type: lncRNA Chromosome: chr8 Starnd: + Coordinate: Start Site(bp): 131308545 End Site(bp): 131317632 External Links: ENSG00000253507

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD2 chr15 89087459 89202355 + AC010132.3 chr7 42909273 42932174 - CGGBP1 chr3 88051944 88149885 - FAM120AOS chr9 93431441 93453581 - GLG1 chr16 74447427 74607144 - GPR61 chr1 109539872 109548406 + HNRNPD chr4 82352498 82374503 - LUZP1 chr1 23084023 23177808 - MARCKSL1 chr1 32333839 32336233 - MEX3D chr19 1554669 1568058 - MTCH1 chr6 36968141 36986298 - MTRNR2L12 chr3 96617188 96618236 - POLD2 chr7 44114681 44124358 - POLI chr18 54269404 54321266 + PSMA2 chr7 42916861 42932185 - RALA chr7 39623565 39708120 + RPS27A chr2 55231903 55235853 + SHPK chr17 3608240 3636250 - SINHCAF chr12 31280584 31327058 - TCAP chr17 39665349 39666554 + VRTN chr14 74303069 74360008 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.