exRNAdisease

Entry Detail

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General Information

Database ID: exR0754034 RNA Name: AC108134.2 RNA Type: lncRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 3156736 End Site(bp): 3157483 External Links: ENSG00000261889

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATP13A1 chr19 19645198 19663676 - NPIPB5 chr16 22479121 22536521 + HSPA1A chr6 31815543 31817946 + JPT2 chr16 1678256 1702280 + AP000350.4 chr22 23862188 23895223 + TSPAN17 chr5 176647387 176659054 + TMEM131 chr2 97756333 97995948 - FLNB chr3 58008400 58172251 + GAPDH chr12 6534512 6538374 + HSP90B1 chr12 103930107 103953645 + MYBBP1A chr17 4538897 4555631 - ATP5MC3 chr2 175176258 175184607 - FOXP4 chr6 41546426 41602384 + NARF chr17 82458180 82490537 + PDF chr16 69326913 69330588 - GTF3C1 chr16 27459555 27549913 - MRPL52 chr14 22829879 22835037 + RPS3 chr11 75399515 75422280 + ALDH2 chr12 111766887 111817532 + WDR5 chr9 134135365 134159968 + PCNA chr20 5114953 5126626 - SLK chr10 103967140 104029233 + CKB chr14 103519667 103522833 - DHCR7 chr11 71428193 71452868 - SNRNP70 chr19 49085419 49108605 + SULT1A1 chr16 28605196 28623625 - UBE2A chrX 119574536 119591083 + IRS4 chrX 108732482 108736409 - RPL27 chr17 42998273 43002959 + B4GALNT2 chr17 49132460 49176840 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-216a-5p chr2 55989020 55989041 - hsa-miR-125b-5p chr21 16590253 16590274 + hsa-miR-125a-5p chr19 51693268 51693291 + hsa-miR-4319 chr18 44970140 44970156 - hsa-miR-7151-5p chr10 67403388 67403410 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.