exRNAdisease

Entry Detail

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General Information

Database ID: exR0754154 RNA Name: AF117829.1 RNA Type: lncRNA Chromosome: chr8 Starnd: - Coordinate: Start Site(bp): 89585872 End Site(bp): 89757812 External Links: ENSG00000251136

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTB chr7 5527148 5563784 - AURKAIP1 chr1 1373730 1375495 - BUB3 chr10 123154402 123170467 + C12orf45 chr12 104986316 105074197 + DNAJC30 chr7 73680918 73683453 - GMPR chr6 16238587 16295549 + KLHDC8B chr3 49171598 49176486 + MLLT3 chr9 20341669 20622518 - NFKB1 chr4 102501331 102617302 + PDCD6 chr5 271621 314974 + RNGTT chr6 88609897 88963618 - SGSM3 chr22 40370591 40410289 + SORD chr15 45023181 45077185 + SRRT chr7 100875103 100888664 + ST13 chr22 40824535 40856639 - TAOK1 chr17 29390464 29551904 + WDR55 chr5 140664676 140674124 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.