exRNAdisease

Entry Detail

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General Information

Database ID: exR0754166 RNA Name: AL021707.2 RNA Type: lncRNA Chromosome: chr22 Starnd: - Coordinate: Start Site(bp): 38667585 End Site(bp): 38681847 External Links: ENSG00000228274

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PUM2 chr2 20248691 20352234 - DHCR7 chr11 71428193 71452868 - ATP7A chrX 77910656 78050395 + B3GNT7 chr2 231395710 231401164 + ACTR1B chr2 97655939 97664044 - RPL27A chr11 8682788 8714759 + RNF11 chr1 51236273 51273447 + GDI2 chr10 5765223 5842132 - CTDNEP1 chr17 7243591 7252491 - NUP107 chr12 68686951 68745809 + PRCC chr1 156750610 156800815 + SETSIP chr1 92074533 92075441 - NKX2-3 chr10 99532942 99536524 + PANX1 chr11 94128841 94181968 + CDK6 chr7 92604921 92836594 - FAM219B chr15 74899992 74906883 - WDFY3 chr4 84669610 84966391 - DOLPP1 chr9 129081111 129090438 + TNFRSF14 chr1 2555639 2565382 + GAPDH chr12 6534512 6538374 + SH2B2 chr7 102285091 102321711 + LONP1 chr19 5691834 5720572 - PKD1 chr16 2088708 2135898 - TUBA1A chr12 49184795 49189080 - GTPBP1 chr22 38705742 38738299 + GJA1 chr6 121435595 121449727 + PSTK chr10 122954381 122997513 + TMEM130 chr7 98846488 98870771 - RHOG chr11 3826978 3840959 - TSPAN3 chr15 77041404 77083984 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC068831.7 chr15 91022766 91023200 + AL021707.1 chr22 38739003 38749041 + LINC00467 chr1 211382736 211435570 + MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.