exRNAdisease

Entry Detail

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General Information

Database ID: exR0754257 RNA Name: AL135925.1 RNA Type: lncRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 79825902 End Site(bp): 79827602 External Links: ENSG00000272447

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD12 chr20 25294742 25390835 - AC010422.3 chr19 12643831 12648397 - ALPK3 chr15 84816680 84873482 + ARFIP2 chr11 6474683 6481479 - ARHGAP4 chrX 153907367 153934999 - BFAR chr16 14632931 14669236 + C11orf24 chr11 68261338 68272001 - CHAF1B chr21 36385392 36419015 + COA4 chr11 73872667 73876901 - CREB1 chr2 207529737 207605988 + DERA chr12 15911302 16037381 + DGCR8 chr22 20080232 20111877 + GLYR1 chr16 4803203 4847288 - HMGB1 chr13 30456704 30617597 - MBD2 chr18 54151606 54224669 - MED29 chr19 39391303 39400641 + MTRNR2L8 chr11 10507894 10509186 - PARVB chr22 43999211 44172949 + PFKL chr21 44300051 44327376 + PROSER1 chr13 39009865 39038089 - RGS10 chr10 119499817 119542719 - SBNO1 chr12 123289109 123364847 - SMC1A chrX 53374149 53422728 - SNX5 chr20 17941597 17968980 - SPTLC2 chr14 77505997 77616773 - TRMT2A chr22 20111875 20117392 - VCP chr9 35056064 35072627 - ZDHHC2 chr8 17156482 17224799 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-8072 chr12 123364814 123364833 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020663.1 chr16 4730115 4752565 - LINC00863 chr10 87341685 87357882 + MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.