exRNAdisease

Entry Detail

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General Information

Database ID: exR0754270 RNA Name: AL136985.3 RNA Type: lncRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 58715609 End Site(bp): 58771295 External Links: ENSG00000283445

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MTRNR2L11 chr1 237943724 237945275 - SLC7A1 chr13 29509414 29595688 - PBX1 chr1 164555584 164899296 + MFSD13A chr10 102461395 102477045 + GTPBP1 chr22 38705742 38738299 + RFLNB chr17 439978 445939 - ARHGAP35 chr19 46860997 47005077 + WDR90 chr16 649311 667833 + SYVN1 chr11 65121780 65134533 - ARID1A chr1 26693236 26782104 + ARFRP1 chr20 63698642 63708025 - CRK chr17 1420689 1463162 - COCH chr14 30874514 30895065 + AL133352.1 chr10 100505628 100529881 - GRB10 chr7 50590063 50793462 - POGZ chr1 151402724 151459494 - NFATC2IP chr16 28950807 28967097 + NDUFB8 chr10 100523740 100530000 - DCHS2 chr4 154231742 154491799 - NPIPB12 chr16 29483642 29505999 - SNRNP70 chr19 49085419 49108605 + ACTG1 chr17 81509971 81523847 - MT-ND5 chrMT 12337 14148 + SLIT2 chr4 20251905 20620561 + PIGW chr17 36534987 36539310 + MT-ND6 chrMT 14149 14673 - FAHD2A chr2 95402708 95416616 + GGA3 chr17 75236599 75262363 - SHMT2 chr12 57229573 57234935 + DAZAP1 chr19 1407569 1435687 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL021707.1 chr22 38739003 38749041 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.