exRNAdisease

Entry Detail

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General Information

Database ID: exR0754365 RNA Name: AL358472.3 RNA Type: lncRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 153966516 End Site(bp): 153966930 External Links: ENSG00000273026

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-26a-5p chr3 37969413 37969434 + hsa-miR-26b-5p chr2 218402657 218402677 + hsa-miR-199a-3p chr1 172144554 172144575 - hsa-miR-122-5p chr18 58451088 58451109 + hsa-miR-584-5p chr5 149062373 149062394 - hsa-miR-199b-3p chr9 128244745 128244766 - hsa-miR-371a-5p chr19 53787680 53787699 + hsa-miR-574-5p chr4 38868056 38868078 + hsa-miR-654-3p chr14 101040269 101040290 + hsa-miR-888-5p chrX 145994830 145994850 - hsa-miR-1297 chr13 54311981 54311997 - hsa-miR-3129-5p chr2 189133082 189133103 - hsa-miR-4465 chr6 140683855 140683876 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.