exRNAdisease

Entry Detail

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General Information

Database ID: exR0754377 RNA Name: AL359924.1 RNA Type: lncRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 237862175 End Site(bp): 237928321 External Links: ENSG00000237250

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABRACL chr6 139028745 139043302 + ACTA1 chr1 229431245 229434098 - ACTB chr7 5527148 5563784 - ACTC1 chr15 34790230 34795549 - ACTG1 chr17 81509971 81523847 - AKR1A1 chr1 45550543 45570049 + AC008878.3 chr19 7382834 7470241 + AC114490.3 chr1 34974356 34985313 - ACTG2 chr2 73892314 73919865 + ADA chr20 44619522 44652233 - ADAM8 chr10 133262420 133276868 - AK4 chr1 65147549 65232145 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7a-5p chr9 94175962 94175983 + hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-326 chr11 75335108 75335127 - hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-493-3p chr14 100869116 100869137 + hsa-miR-588 chr6 126484646 126484666 + hsa-miR-371a-5p chr19 53787680 53787699 + hsa-miR-330-5p chr19 45639049 45639070 - hsa-miR-942-5p chr1 117094655 117094676 + hsa-miR-1287-5p chr10 98395271 98395292 - hsa-miR-3200-5p chr22 30731569 30731590 + hsa-miR-4701-5p chr12 48772014 48772035 - hsa-miR-5691 chr11 9090350 9090371 - hsa-miR-6805-3p chr19 55388220 55388242 + hsa-miR-6838-5p chr7 44073407 44073428 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.