exRNAdisease

Entry Detail

General Information

Database ID:

exR0754480

RNA Name:

AP000766.1

RNA Type:

lncRNA

Chromosome:

chr11

Starnd:

-

Coordinate:

Start Site(bp):

107312132

End Site(bp):

107316271

External Links:

ENSG00000261098

Disease Information

Disease Name:	Glioblastoma Multiforme
Disease Category:	Cancers
MeSH ID:	D005909
Type:	Neoplasms/Neoplasms, Glandular and Epithelial
Alias:	Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID:	GSE106804
Description:	Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:	Cancer vs Control
Case Disease Type:	Glioblastoma Multiforme
Case Disease SubType:	NA
Case Sample:	Glioblastoma Multiforme
Control Sample:	Healthy
Number of Case:	13
Number of Control:	6
Number of Samples:	19

Regulatory Relationship

mRNA targets:

NA

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-let-7a-5p	chr9	94175962	94175983	+
hsa-let-7b-5p	chr22	46113691	46113712	+
hsa-let-7c-5p	chr21	16539838	16539859	+
hsa-let-7d-5p	chr9	94178841	94178862	+
hsa-let-7e-5p	chr19	51692793	51692814	+
hsa-let-7f-5p	chrX	53557246	53557267	-
hsa-miR-98-5p	chrX	53556299	53556320	-
hsa-let-7g-5p	chr3	52268336	52268357	-
hsa-let-7i-5p	chr12	62603691	62603712	+
hsa-miR-1224-5p	chr3	184241405	184241423	+
hsa-miR-4458	chr5	8460933	8460951	+
hsa-miR-4500	chr13	87618671	87618687	-

circRNA targets:

NA

lncRNA targets:

NA

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	29330365
Title:	Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:	Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:	Nat Commun. 2018 Jan 12;9(1):175.
Description:	Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.