exRNAdisease

Entry Detail

---



General Information

Database ID: exR0754581 RNA Name: CYTOR RNA Type: lncRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 87454781 End Site(bp): 87636740 External Links: ENSG00000222041

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADGRG2 chrX 18989307 19122637 - AHCY chr20 34280268 34311802 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-105-5p chrX 152394458 152394480 - hsa-miR-128-3p chr2 135665446 135665466 + hsa-miR-193a-3p chr17 31560050 31560071 + hsa-miR-376c-3p chr14 101039732 101039752 + hsa-miR-193b-3p chr16 14304017 14304038 + hsa-miR-513a-5p chrX 147213538 147213555 - hsa-miR-3681-3p chr2 12199174 12199195 + hsa-miR-642b-3p chr19 45674941 45674962 - hsa-miR-2467-3p chr2 239351732 239351753 - hsa-miR-642a-3p chr19 45674978 45674999 + hsa-miR-873-3p chr9 28888889 28888910 - hsa-miR-216a-3p chr2 55988981 55989002 - hsa-miR-7853-5p chr6 6169380 6169400 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC017002.1 chr2 111607841 111612518 + AC133644.3 chr2 87455476 87767359 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.