exRNAdisease

Entry Detail

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General Information

Database ID: exR0754600 RNA Name: EBLN3P RNA Type: lncRNA Chromosome: chr9 Starnd: + Coordinate: Start Site(bp): 37079645 End Site(bp): 37090928 External Links: ENSG00000281649

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AARS2 chr6 44298731 44313347 - AC007192.1 chr19 18153158 18178117 + AC010422.3 chr19 12643831 12648397 - AAR2 chr20 36236459 36270918 + ABCB7 chrX 75051048 75156732 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-24-3p chr9 95086064 95086085 + hsa-miR-101-3p chr1 65058442 65058462 - hsa-miR-204-5p chr9 70810031 70810052 - hsa-miR-211-5p chr15 31065095 31065116 - hsa-miR-144-3p chr17 28861548 28861567 - hsa-miR-186-5p chr1 71067681 71067702 - hsa-miR-374a-5p chrX 74287325 74287346 - hsa-miR-323a-3p chr14 101025782 101025802 + hsa-miR-655-3p chr14 101049610 101049631 + hsa-miR-340-5p chr5 180015361 180015382 - hsa-miR-374b-5p chrX 74218587 74218608 - hsa-miR-1185-5p chr14 101044212 101044232 + hsa-miR-3187-3p chr19 813627 813646 + hsa-miR-3679-5p chr2 134127130 134127152 + hsa-miR-374c-5p chrX 74218561 74218582 + hsa-miR-873-3p chr9 28888889 28888910 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.