exRNAdisease

Entry Detail

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General Information

Database ID: exR0754640 RNA Name: HCG11 RNA Type: lncRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 26521709 End Site(bp): 26527404 External Links: ENSG00000228223

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-654-3p chr14 101040269 101040290 + hsa-miR-1297 chr13 54311981 54311997 - hsa-miR-576-5p chr4 109488713 109488734 + hsa-miR-129-2-3p chr11 43581450 43581471 + hsa-miR-656-3p chr14 101066766 101066786 + hsa-miR-579-3p chr5 32394392 32394414 - hsa-miR-522-3p chr19 53751264 53751285 + hsa-miR-539-3p chr14 101047369 101047390 + hsa-miR-144-3p chr17 28861548 28861567 - hsa-miR-485-3p chr14 101055464 101055485 + hsa-miR-26a-5p chr3 37969413 37969434 + hsa-miR-4424 chr1 178677763 178677784 + hsa-miR-1277-5p chrX 118386401 118386424 + hsa-miR-129-1-3p chr7 128207920 128207941 + hsa-miR-376c-3p chr14 101039732 101039752 + hsa-miR-3145-3p chr6 138435223 138435246 - hsa-miR-520h chr19 53742566 53742587 + hsa-miR-382-3p chr14 101054352 101054372 + hsa-miR-3163 chr11 66934476 66934497 - hsa-miR-483-3p chr11 2134142 2134162 - hsa-miR-499a-5p chr20 34990408 34990428 + hsa-miR-520g-3p chr19 53722220 53722243 + hsa-miR-4465 chr6 140683855 140683876 + hsa-miR-28-3p chr3 188688834 188688855 + hsa-miR-7853-5p chr6 6169380 6169400 - hsa-miR-4637 chr5 14825932 14825953 - hsa-miR-105-5p chrX 152394458 152394480 - hsa-miR-224-3p chrX 151958584 151958606 - hsa-miR-26b-5p chr2 218402657 218402677 + hsa-miR-545-5p chrX 74287164 74287185 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.