exRNAdisease

Entry Detail

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General Information

Database ID: exR0754641 RNA Name: HCG18 RNA Type: lncRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 30286690 End Site(bp): 30327382 External Links: ENSG00000231074

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKT1S1 chr19 49869033 49878459 - AKT2 chr19 40230317 40285536 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-545-5p chrX 74287164 74287185 - hsa-miR-324-5p chr17 7223343 7223364 - hsa-miR-4677-3p chr1 243346225 243346246 + hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-148b-3p chr12 54337278 54337299 + hsa-miR-4739 chr17 79707216 79707240 - hsa-miR-3174 chr15 90006764 90006786 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-148a-3p chr7 25949922 25949943 - hsa-miR-449c-5p chr5 55172313 55172337 - hsa-miR-449a chr5 55170586 55170607 - hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-4756-5p chr20 54068452 54068474 - hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-499a-5p chr20 34990408 34990428 + hsa-miR-3614-5p chr17 56891319 56891341 - hsa-miR-495-3p chr14 101033804 101033825 + hsa-miR-3605-5p chr1 33332449 33332471 - hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-5688 chr3 85385761 85385782 + hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-6838-5p chr7 44073407 44073428 - hsa-miR-4508 chr15 23562107 23562123 - hsa-miR-34b-5p chr11 111512950 111512972 + hsa-miR-2682-5p chr1 98045307 98045329 - hsa-miR-499b-5p chr20 34990443 34990463 - hsa-miR-34c-5p chr11 111513451 111513473 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022157.1 chrX 57121662 57127243 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.