exRNAdisease

Entry Detail

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General Information

Database ID: exR0754677 RNA Name: LINC00265 RNA Type: lncRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 39733430 End Site(bp): 39793092 External Links: ENSG00000188185

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADCY9 chr16 3953387 4116442 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7a-5p chr9 94175962 94175983 + hsa-let-7b-5p chr22 46113691 46113712 + hsa-let-7c-5p chr21 16539838 16539859 + hsa-let-7d-5p chr9 94178841 94178862 + hsa-let-7e-5p chr19 51692793 51692814 + hsa-let-7f-5p chrX 53557246 53557267 - hsa-miR-98-5p chrX 53556299 53556320 - hsa-let-7g-5p chr3 52268336 52268357 - hsa-let-7i-5p chr12 62603691 62603712 + hsa-miR-34b-5p chr11 111512950 111512972 + hsa-miR-485-5p chr14 101055427 101055448 + hsa-miR-556-5p chr1 162342561 162342582 + hsa-miR-1294 chr5 154347153 154347174 + hsa-miR-449c-5p chr5 55172313 55172337 - hsa-miR-2682-5p chr1 98045307 98045329 - hsa-miR-4458 chr5 8460933 8460951 + hsa-miR-4500 chr13 87618671 87618687 - hsa-miR-5009-3p chr15 89883949 89883970 - hsa-miR-873-3p chr9 28888889 28888910 - hsa-miR-6884-5p chr17 40026383 40026404 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.