exRNAdisease

Entry Detail

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General Information

Database ID: exR0754682 RNA Name: LINC00324 RNA Type: lncRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 8220642 End Site(bp): 8224043 External Links: ENSG00000178977

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTG1 chr17 81509971 81523847 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-154-3p chr14 101059805 101059826 + hsa-miR-362-5p chrX 50008968 50008991 + hsa-miR-487a-3p chr14 101052494 101052515 + hsa-miR-516b-5p chr19 53736860 53736881 + hsa-miR-769-5p chr19 46018961 46018982 + hsa-miR-214-5p chr1 172138857 172138878 - hsa-miR-151a-5p chr8 140732623 140732643 - hsa-miR-545-5p chrX 74287164 74287185 - hsa-miR-151b chr14 100109438 100109455 - hsa-miR-3126-5p chr2 69103691 69103712 + hsa-miR-3164 chr11 69083185 69083206 + hsa-miR-500b-5p chrX 50010682 50010699 + hsa-miR-3200-5p chr22 30731569 30731590 + hsa-miR-6820-3p chr22 37967603 37967624 + hsa-miR-6875-5p chr7 100868041 100868061 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.