exRNAdisease

Entry Detail

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General Information

Database ID: exR0754730 RNA Name: LINC00667 RNA Type: lncRNA Chromosome: chr18 Starnd: + Coordinate: Start Site(bp): 5237826 End Site(bp): 5290608 External Links: ENSG00000263753

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDH18A1 chr10 95605941 95656711 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-19a-3p chr13 91350939 91350961 + hsa-miR-19b-3p chr13 91351245 91351267 + hsa-miR-181a-5p chr1 198859108 198859130 - hsa-miR-181b-5p chr9 124693725 124693747 + hsa-miR-181c-5p chr19 13874725 13874746 + hsa-miR-200b-3p chr1 1167160 1167181 + hsa-miR-143-3p chr5 149428978 149428998 + hsa-miR-126-5p chr9 136670616 136670636 + hsa-miR-154-5p chr14 101059769 101059790 + hsa-miR-200c-3p chr12 6963742 6963764 + hsa-miR-429 chr1 1169055 1169076 + hsa-miR-181d-5p chr19 13874910 13874932 + hsa-miR-4262 chr2 11836943 11836959 - hsa-miR-4770 chrX 6383907 6383924 - hsa-miR-6088 chr19 45436654 45436673 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.