exRNAdisease

Entry Detail

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General Information

Database ID: exR0754790 RNA Name: LINC01184 RNA Type: lncRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 127939152 End Site(bp): 128083172 External Links: ENSG00000245937

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACAP1 chr17 7336529 7351477 + AC024592.3 chr19 5866171 5903787 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-193a-3p chr17 31560050 31560071 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-374a-5p chrX 74287325 74287346 - hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-193b-3p chr16 14304017 14304038 + hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-516b-5p chr19 53736860 53736881 + hsa-miR-425-5p chr3 49020199 49020221 - hsa-miR-374b-5p chrX 74218587 74218608 - hsa-miR-216b-5p chr2 56000764 56000785 - hsa-miR-3187-3p chr19 813627 813646 + hsa-miR-4524a-5p chr17 69099606 69099627 - hsa-miR-4524b-5p chr17 69099570 69099590 + hsa-miR-6838-5p chr7 44073407 44073428 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC133644.3 chr2 87455476 87767359 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.