exRNAdisease

Entry Detail

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General Information

Database ID: exR0755056 RNA Name: MIR194-2HG RNA Type: lncRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 64889560 End Site(bp): 64893449 External Links: ENSG00000229719

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-192-5p chr11 64891203 64891223 - hsa-miR-215-5p chr1 220117916 220117936 - hsa-miR-193a-3p chr17 31560050 31560071 + hsa-miR-328-3p chr16 67202327 67202348 - hsa-miR-193b-3p chr16 14304017 14304038 + hsa-miR-516b-5p chr19 53736860 53736881 + hsa-miR-760 chr1 93846880 93846899 + hsa-miR-3180-3p chr16 16309936 16309957 + hsa-miR-3196 chr20 63238788 63238805 + hsa-miR-3180 chr16 15154949 15154967 - hsa-miR-3173-5p chr14 95137961 95137982 - hsa-miR-3064-5p chr17 64500817 64500837 - hsa-miR-6504-5p chr16 81611352 81611372 + hsa-miR-6799-3p chr19 49791912 49791934 + hsa-miR-6816-5p chr22 20114726 20114746 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.