exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755080 RNA Name: NORAD RNA Type: lncRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 36045618 End Site(bp): 36051018 External Links: ENSG00000260032

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASS chr7 122073549 122144255 - ADIPOR1 chr1 202940826 202958572 - AGRN chr1 1020120 1056118 + AKR1B1 chr7 134442356 134459284 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-132-5p chr17 2049965 2049986 - hsa-miR-576-5p chr4 109488713 109488734 + hsa-miR-496 chr14 101060628 101060649 + hsa-miR-888-5p chrX 145994830 145994850 - hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-199b-3p chr9 128244745 128244766 - hsa-miR-302c-3p chr4 112648366 112648388 - hsa-miR-1306-5p chr22 20086072 20086093 + hsa-miR-1297 chr13 54311981 54311997 - hsa-miR-106a-5p chrX 134170244 134170266 - hsa-miR-371a-5p chr19 53787680 53787699 + hsa-miR-4424 chr1 178677763 178677784 + hsa-miR-3187-3p chr19 813627 813646 + hsa-miR-4262 chr2 11836943 11836959 - hsa-miR-106b-5p chr7 100094043 100094063 - hsa-miR-384 chrX 76919285 76919304 - hsa-miR-302d-3p chr4 112648006 112648028 - hsa-miR-1245b-5p chr2 188978133 188978153 - hsa-miR-181b-5p chr9 124693725 124693747 + hsa-miR-324-3p chr17 7223308 7223330 - hsa-miR-520c-3p chr19 53707506 53707527 + hsa-miR-520d-5p chr19 53720111 53720130 + hsa-miR-373-3p chr19 53788748 53788770 + hsa-miR-378e chr5 170028545 170028563 + hsa-miR-17-5p chr13 91350618 91350640 + hsa-miR-511-3p chr10 17845160 17845179 + hsa-miR-518d-5p chr19 53734892 53734913 + hsa-miR-580-3p chr5 36147907 36147928 - hsa-miR-485-3p chr14 101055464 101055485 + hsa-miR-20b-5p chrX 134169850 134169872 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005082.1 chr7 23205787 23208045 + AC099499.2 chr5 25188059 25188778 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.