exRNAdisease

Entry Detail

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General Information

Database ID: exR0755085 RNA Name: NUTM2B-AS1 RNA Type: lncRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 79661394 End Site(bp): 79826594 External Links: ENSG00000225484

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC058822.1 chr4 53377839 54295272 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-96-5p chr7 129774739 129774761 - hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-107 chr10 89592756 89592778 - hsa-miR-148a-3p chr7 25949922 25949943 - hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-152-3p chr17 48037174 48037194 - hsa-miR-126-5p chr9 136670616 136670636 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-148b-3p chr12 54337278 54337299 + hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-1271-5p chr5 176367960 176367981 + hsa-miR-3164 chr11 69083185 69083206 + hsa-miR-4524a-5p chr17 69099606 69099627 - hsa-miR-5094 chr15 89850690 89850711 - hsa-miR-4524b-5p chr17 69099570 69099590 + hsa-miR-6820-3p chr22 37967603 37967624 + hsa-miR-6838-5p chr7 44073407 44073428 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008957.1 chr5 36666214 36725195 - AC023509.1 chr12 53441741 53467528 + AL132656.2 chr10 79660891 79677996 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.