exRNAdisease

Entry Detail

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General Information

Database ID: exR0755101 RNA Name: PCBP2-OT1 RNA Type: lncRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 53464468 End Site(bp): 53465057 External Links: ENSG00000282977

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADPGK chr15 72751369 72785846 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-491-5p chr9 20716120 20716141 + hsa-miR-432-5p chr14 100884496 100884518 + hsa-miR-519c-5p chr19 53686484 53686505 + hsa-miR-518f-5p chr19 53700030 53700051 + hsa-miR-526a-5p chr19 53726928 53726949 + hsa-miR-296-3p chr20 58817626 58817647 - hsa-miR-541-5p chr14 101064504 101064528 + hsa-miR-523-5p chr19 53698400 53698421 + hsa-miR-518e-5p chr19 53729853 53729874 + hsa-miR-522-5p chr19 53751226 53751247 + hsa-miR-519a-5p chr19 53752411 53752432 + hsa-miR-519b-5p chr19 53695225 53695246 + hsa-miR-520c-5p chr19 53707468 53707489 + hsa-miR-518d-5p chr19 53734892 53734913 + hsa-miR-873-3p chr9 28888889 28888910 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.