exRNAdisease

Entry Detail

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General Information

Database ID: exR0755167 RNA Name: SNHG12 RNA Type: lncRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 28578538 End Site(bp): 28583132 External Links: ENSG00000197989

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC118553.2 chr1 99970011 100083321 + AC138969.1 chr16 16317444 16350590 + AKR1B1 chr7 134442356 134459284 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-199a-5p chr1 172144592 172144614 - hsa-miR-199b-5p chr9 128244783 128244805 - hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-494-3p chr14 101029681 101029702 + hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-503-5p chrX 134546371 134546393 - hsa-miR-620 chr12 116148575 116148594 - hsa-miR-129-1-3p chr7 128207920 128207941 + hsa-miR-129-2-3p chr11 43581450 43581471 + hsa-miR-320b chr1 224257049 224257070 - hsa-miR-320c chr18 24321716 24321735 + hsa-miR-1301-3p chr2 25328651 25328674 - hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-320d chr13 40727828 40727846 - hsa-miR-4429 chr2 11540652 11540671 - hsa-miR-5047 chr17 64501230 64501250 - hsa-miR-6512-3p chr2 177313811 177313832 - hsa-miR-6720-5p chr6 1390359 1390381 - hsa-miR-6838-5p chr7 44073407 44073428 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.