exRNAdisease

Entry Detail

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General Information

Database ID: exR0755169 RNA Name: SNHG25 RNA Type: lncRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 64145970 End Site(bp): 64146476 External Links: ENSG00000266402

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - ACTG1 chr17 81509971 81523847 - ADSL chr22 40346500 40390463 + AL022238.4 chr22 40346529 40410054 + AKIRIN2 chr6 87674860 87702233 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-330-3p chr19 45639009 45639031 - hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-329-3p chr14 101026834 101026855 + hsa-miR-489-3p chr7 93483947 93483968 - hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-663a chr20 26208243 26208264 - hsa-miR-296-3p chr20 58817626 58817647 - hsa-miR-362-3p chrX 50009005 50009026 + hsa-miR-1251-5p chr12 97491913 97491933 + hsa-miR-1307-3p chr10 103394301 103394322 - hsa-miR-1908-5p chr11 61815209 61815229 - hsa-miR-579-5p chr5 32394430 32394451 - hsa-miR-6787-5p chr17 82236673 82236694 + hsa-miR-6838-5p chr7 44073407 44073428 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.