exRNAdisease

Entry Detail

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General Information

Database ID: exR0755171 RNA Name: SNHG8 RNA Type: lncRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 118278709 End Site(bp): 118285316 External Links: ENSG00000269893

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC048338.1 chr12 122207779 122266423 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - AFG1L chr6 108294991 108526796 + ALDOA chr16 30064164 30070457 + AC024592.3 chr19 5866171 5903787 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-149-5p chr2 240456015 240456037 + hsa-miR-154-5p chr14 101059769 101059790 + hsa-miR-384 chrX 76919285 76919304 - hsa-miR-494-3p chr14 101029681 101029702 + hsa-miR-522-3p chr19 53751264 53751285 + hsa-miR-588 chr6 126484646 126484666 + hsa-miR-620 chr12 116148575 116148594 - hsa-miR-411-5p chr14 101023340 101023360 + hsa-miR-656-3p chr14 101066766 101066786 + hsa-miR-542-3p chrX 134541364 134541385 - hsa-miR-425-5p chr3 49020199 49020221 - hsa-miR-371a-5p chr19 53787680 53787699 + hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-224-3p chrX 151958584 151958606 - hsa-miR-4701-5p chr12 48772014 48772035 - hsa-miR-506-5p chrX 147230788 147230809 - hsa-miR-873-3p chr9 28888889 28888910 - hsa-miR-7151-5p chr10 67403388 67403410 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC068205.2 chr11 43578889 43840030 + AC139149.1 chr17 81514047 81527776 + AL133215.2 chr10 101060029 101061005 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.