exRNAdisease

Entry Detail

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General Information

Database ID: exR0755258 RNA Name: A1BG RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 58345178 End Site(bp): 58353492 External Links: ENSG00000121410

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTR8 chr3 53867066 53882152 - AKT1 chr14 104769349 104795751 - ARMC5 chr16 31458080 31467166 + C2orf49 chr2 105337532 105349211 + CCT7 chr2 73233420 73253021 + CD70 chr19 6583183 6604103 - GAPDH chr12 6534512 6538374 + PBX2 chr6 32184733 32190202 - PGM1 chr1 63593411 63660245 + PREX1 chr20 48624252 48827999 - RNF135 chr17 30970984 30999911 + RPL19 chr17 39200283 39204732 + RPL37 chr5 40825262 40835222 - SRP14 chr15 40035690 40039181 - TMSB10 chr2 84905656 84906671 + UNC45A chr15 90930180 90954093 + WDR18 chr19 984271 998438 + WDR6 chr3 49007062 49015953 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012313.3 chr19 58346854 58362751 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.