exRNAdisease

Entry Detail

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General Information

Database ID: exR0755262 RNA Name: AAAS RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 53307456 End Site(bp): 53324864 External Links: ENSG00000094914

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MSI1 chr12 120341330 120369164 - RPL11 chr1 23691742 23696835 + RPLP2 chr11 809965 812880 + MIF chr22 23894383 23895227 + MRPS10 chr6 42206807 42217861 - RCSD1 chr1 167630093 167708696 + LRCH4 chr7 100574011 100586129 - LRP2 chr2 169127109 169362534 - MEX3C chr18 51174550 51218304 - MTRNR2L12 chr3 96617188 96618236 - MTA1 chr14 105419820 105470729 + B2M chr15 44711487 44718877 + CDC25B chr20 3786772 3806121 + SFPQ chr1 35176378 35193145 - ZNF207 chr17 32350117 32381886 + VPS41 chr7 38722974 38932394 - RPL13 chr16 89560657 89566828 + METTL16 chr17 2405562 2511891 - MAPK14 chr6 36027677 36111236 + CD99 chrX 2691187 2741309 + YBX3 chr12 10699089 10723323 - AP000350.4 chr22 23862188 23895223 + PKM chr15 72199029 72231822 - FRAS1 chr4 78057323 78544269 + LRIG1 chr3 66378797 66501263 - RACK1 chr5 181236897 181248096 - ALDOA chr16 30064164 30070457 + MYL6 chr12 56158161 56163496 + NBR1 chr17 43170481 43211689 + LAMA5 chr20 62307955 62367312 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC069281.2 chr7 100572232 100578700 - PCAT6 chr1 202810954 202812156 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.