exRNAdisease

Entry Detail

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General Information

Database ID: exR0755263 RNA Name: AACS RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 125065434 End Site(bp): 125143333 External Links: ENSG00000081760

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NPM3 chr10 101781325 101783413 - FGFR2 chr10 121478334 121598458 - PDXK chr21 43719094 43762307 + EXOC6B chr2 72175984 72826041 - SIPA1L2 chr1 232397965 232561558 - NOP14 chr4 2937933 2963406 - ZNF579 chr19 55576774 55580848 - MTERF4 chr2 241072169 241102332 - EIF6 chr20 35278911 35284985 - CITED2 chr6 139371807 139374648 - EME1 chr17 50373220 50381483 + PHLDA1 chr12 76025447 76033932 - RPLP2 chr11 809965 812880 + ZBTB44 chr11 130226677 130314917 - KLHL21 chr1 6590724 6614607 - TMEM259 chr19 1009648 1021179 - RPS5 chr19 58386400 58394806 + PCBP2 chr12 53452102 53481162 + VCP chr9 35056064 35072627 - BRD9 chr5 850291 892801 - TRIM13 chr13 49995888 50020481 + SUPT20H chr13 37009312 37059713 - AIFM2 chr10 70098223 70132934 - AL121753.1 chr20 35267885 35280043 - OST4 chr2 27070472 27071654 - HSP90AB1 chr6 44246166 44253888 + BCKDK chr16 31106107 31112791 + AAMP chr2 218264123 218270257 - SELENOH chr11 57741250 57743554 + BUD31 chr7 99408641 99419616 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC023509.1 chr12 53441741 53467528 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.