exRNAdisease

Entry Detail

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General Information

Database ID: exR0755271 RNA Name: AARS2 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 44298731 End Site(bp): 44313347 External Links: ENSG00000124608

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand COX5A chr15 74919791 74938083 - HSP90AB1 chr6 44246166 44253888 + DENND5A chr11 9138825 9265350 - SFT2D3 chr2 127701497 127705242 + USP22 chr17 20999596 21043760 - SRSF5 chr14 69726900 69772005 + FAM83D chr20 38926312 38953106 + RRP12 chr10 97356358 97426076 - WDR27 chr6 169457212 169702067 - KPNB1 chr17 47649476 47685505 + RAD23A chr19 12945855 12953642 + RBM8A chr1 145917714 145927678 - TIMELESS chr12 56416363 56449426 - MIDN chr19 1248553 1259140 + MT-ND2 chrMT 4470 5511 + GRAMD1A chr19 34994784 35026471 + TM9SF3 chr10 96518110 96587452 - TP53I11 chr11 44885903 44951306 - HSP90B1 chr12 103930107 103953645 + NDFIP1 chr5 142108779 142154440 + USP35 chr11 78188812 78215232 + RPL13 chr16 89560657 89566828 + EIF3C chr16 28688558 28735730 + DPPA4 chr3 109326141 109337572 - ARSA chr22 50622754 50628173 - TBL1XR1 chr3 177019340 177228000 - WDR74 chr11 62832342 62841809 - ORAI3 chr16 30949068 30956461 + PTOV1 chr19 49850735 49860744 + PML chr15 73994673 74047827 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC102953.2 chr7 1464497 1467522 - AL355075.4 chr14 20343048 20343685 - EBLN3P chr9 37079645 37090928 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.