exRNAdisease

Entry Detail

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General Information

Database ID: exR0755272 RNA Name: AARSD1 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 42950526 End Site(bp): 42964498 External Links: ENSG00000266967

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PTMS chr12 6765516 6770952 + KBTBD7 chr13 41189834 41194569 - PPDPF chr20 63520765 63522206 + PPP1CC chr12 110719680 110742939 - BLOC1S5-TXNDC5 chr6 7881522 8064364 - ZNF777 chr7 149431363 149461062 - CALM3 chr19 46601074 46610782 + HIGD2A chr5 176388751 176389761 + RPL35A chr3 197950190 197956610 + HNRNPF chr10 43385617 43409166 - CCNT2 chr2 134918235 134959342 + ERI2 chr16 20780193 20900349 - RPUSD3 chr3 9837849 9844602 - TPT1 chr13 45333471 45341370 - RNPS1 chr16 2253116 2268397 - CALR chr19 12938578 12944489 + PTGES3L-AARSD1 chr17 42950526 42980528 - RNF213 chr17 80260866 80398786 + SASH3 chrX 129779949 129795201 + EDARADD chr1 236348257 236502915 + CST3 chr20 23626706 23638473 - SKI chr1 2228319 2310213 + MRPL13 chr8 120380761 120445402 - TMEM258 chr11 61768501 61792802 - ASB8 chr12 48147789 48181213 - RPL27 chr17 42998273 43002959 + GSPT2 chrX 51743442 51746232 + TXNDC5 chr6 7881517 7910788 - DYNLL1 chr12 120469850 120498493 + TRMU chr22 46330875 46357340 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand Z95114.1 chr22 36071000 36085573 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.