exRNAdisease

Entry Detail

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General Information

Database ID: exR0755275 RNA Name: AATF RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 36948954 End Site(bp): 37056871 External Links: ENSG00000275700

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SSR1 chr6 7268306 7347446 - RPS19 chr19 41860255 41872925 + THY1 chr11 119417378 119424985 - EIF3B chr7 2354086 2380745 + CD74 chr5 150400041 150412929 - CASP2 chr7 143288215 143307696 + BDH1 chr3 197509783 197573323 - RNF113A chrX 119870475 119871733 - RTCA chr1 100266207 100292769 + AP002990.1 chr11 62559603 62591531 - CKB chr14 103519667 103522833 - CLDN23 chr8 8701937 8704096 + RPL8 chr8 144789765 144792587 - VLDLR chr9 2621787 2660056 + ACTB chr7 5527148 5563784 - MT-CO3 chrMT 9207 9990 + RPS6 chr9 19375715 19380236 - NIPA2 chr15 22838641 22868384 + UBA52 chr19 18571730 18577550 + DYNC1H1 chr14 101964573 102056443 + UBALD2 chr17 76265348 76271298 + LSM1 chr8 38163335 38176730 - CIC chr19 42268537 42295797 + PAQR3 chr4 78887127 78939438 - CCNA2 chr4 121816444 121823933 - TMEM258 chr11 61768501 61792802 - ACTR1B chr2 97655939 97664044 - CIT chr12 119685791 119877320 - FAN1 chr15 30890559 30943108 + SRGN chr10 69088103 69104805 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4492 chr11 118910765 118910781 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL355987.4 chr9 136799223 136810042 + NAALADL2-AS2 chr3 175234861 175271096 - SNHG1 chr11 62851984 62855953 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.