exRNAdisease

Entry Detail

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General Information

Database ID: exR0755276 RNA Name: ABAT RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 8674596 End Site(bp): 8784575 External Links: ENSG00000183044

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ARFIP2 chr11 6474683 6481479 - BTNL9 chr5 181040225 181061521 + ESRP1 chr8 94641074 94707466 + HNRNPA1P48 chr16 51553436 51647132 + LSM14B chr20 62122461 62135374 + MEA1 chr6 43011143 43016868 - PTCD2 chr5 72320367 72368395 + RHBDF2 chr17 76470891 76501790 - RPS28 chr19 8321158 8323340 + RPS6 chr9 19375715 19380236 - SENP6 chr6 75601509 75718281 + SNRPD2 chr19 45687454 45692569 - SP2 chr17 47896150 47928957 + SPTLC1 chr9 92000087 92115413 - TMEM9 chr1 201134772 201171574 - USP7 chr16 8892097 8975328 - ZBTB11 chr3 101648889 101677132 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-485-5p chr14 101055427 101055448 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDH1L1-AS2 chr3 126180012 126210169 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.