exRNAdisease

Entry Detail

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General Information

Database ID: exR0755277 RNA Name: ABCA1 RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 104781006 End Site(bp): 104928155 External Links: ENSG00000165029

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand COX5B chr2 97646062 97648383 + EIF3L chr22 37848868 37889407 + EWSR1 chr22 29268009 29300525 + FEN1 chr11 61792911 61797238 + GANAB chr11 62624826 62646726 - GAPDH chr12 6534512 6538374 + HADH chr4 107989714 108035175 + IGF2 chr11 2129112 2141238 - IGF2BP3 chr7 23310209 23470491 - KDM3B chr5 138352685 138437028 + LSMEM1 chr7 112480853 112491062 + LUC7L3 chr17 50719565 50756219 + MPI chr15 74890005 74902219 + NISCH chr3 52455118 52493068 + PIANP chr12 6693792 6700800 - PPRC1 chr10 102132994 102150333 + RPL13A chr19 49487554 49492308 + RPL14 chr3 40457292 40468587 + RPL19 chr17 39200283 39204732 + RPS23 chr5 82273320 82278396 - SEC11A chr15 84669538 84716460 - SHROOM3 chr4 76435229 76783253 + SND1 chr7 127652194 128092609 + UBE2R2 chr9 33817160 33920399 + ZNF217 chr20 53567065 53609907 - ZNF568 chr19 36916329 36998700 + ZNF696 chr8 143289676 143299952 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1294 chr5 154347153 154347174 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.