exRNAdisease

Entry Detail

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General Information

Database ID: exR0755285 RNA Name: ABCB4 RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 87401697 End Site(bp): 87480435 External Links: ENSG00000005471

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB1 chr7 87503017 87713323 - AP1G2 chr14 23559565 23568070 - BASP1 chr5 17065598 17276843 + CENPV chr17 16342534 16353656 - CLDN6 chr16 3014712 3020071 - CUL5 chr11 108008898 108107761 + DDX5 chr17 64498254 64508199 - EIF5A chr17 7306999 7312463 + FXR2 chr17 7591230 7614897 - HNRNPDL chr4 82422564 82430408 - HSPA8 chr11 123057489 123063230 - HTATSF1 chrX 136497079 136512346 + KIF5B chr10 32009015 32056425 - MAF1 chr8 144104461 144107611 + NUAK1 chr12 106063340 106140033 - PAM chr5 102753981 103031105 + PHF14 chr7 10973336 11169630 + RPL5 chr1 92832013 92841924 + SERF2 chr15 43777087 43802589 + SLC39A1 chr1 153959099 153968184 - SNX18 chr5 54517759 54546586 + SPOCK2 chr10 72059034 72089032 - STX7 chr6 132445867 132513198 - TMEM167A chr5 83052846 83077863 - TPT1 chr13 45333471 45341370 - ZNF136 chr19 12163064 12189871 + ZNF385A chr12 54369133 54391298 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.