exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755286 RNA Name: ABCB7 RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 75051048 End Site(bp): 75156732 External Links: ENSG00000131269

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand YWHAZ chr8 100916523 100953388 - DDX5 chr17 64498254 64508199 - MAPKAPK2 chr1 206684944 206734283 + YWHAQ chr2 9583967 9630997 - MT-CO1 chrMT 5904 7445 + CSNK2B chr6 31665236 31670343 + MAGED1 chrX 51803007 51902357 + PBX2 chr6 32184733 32190202 - CCNI chr4 77047155 77075989 - CFL1 chr11 65823022 65862026 - TM7SF3 chr12 26971579 27014434 - ADD1 chr4 2843857 2930076 + AP002990.1 chr11 62559603 62591531 - RARA chr17 40309180 40357643 + RPAIN chr17 5419641 5432876 + RPS12 chr6 132814569 132817564 + IPO5 chr13 97953658 98024296 + NOMO3 chr16 16232528 16294811 + JMJD1C chr10 63167221 63521850 - MEN1 chr11 64803510 64811294 - RAB11A chr15 65726054 65891989 + P4HB chr17 81843161 81860624 - EEF1G chr11 62559596 62574086 - TMSB4X chrX 12975110 12977227 + CAPN15 chr16 527712 554636 + RABEP1 chr17 5282265 5386340 + LPCAT1 chr5 1456480 1523962 - INSIG1 chr7 155297776 155310235 + ANP32B chr9 97983341 98015943 + TMED5 chr1 93149742 93180516 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand EBLN3P chr9 37079645 37090928 + LINC00205 chr21 45288050 45297806 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.