exRNAdisease

Entry Detail

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General Information

Database ID: exR0755294 RNA Name: ABCD3 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 94418389 End Site(bp): 94518666 External Links: ENSG00000117528

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SLC25A6 chrX 1386152 1392113 - RPL13 chr16 89560657 89566828 + ACYP2 chr2 53970838 54305300 + RPL15 chr3 23916545 23924374 + C18orf25 chr18 46173553 46266992 + GFM1 chr3 158644278 158692575 + SH3KBP1 chrX 19533977 19887600 - EGLN2 chr19 40798996 40808434 + MIF chr22 23894383 23895227 + LTA4H chr12 96000753 96043520 - RIC1 chr9 5629025 5776557 + EIF3L chr22 37848868 37889407 + SMIM13 chr6 11093834 11138733 + ZKSCAN8 chr6 28141883 28159460 + NACA chr12 56712427 56731628 - CBX4 chr17 79833156 79839440 - RPS6 chr9 19375715 19380236 - HNRNPR chr1 23303771 23344336 - RPL28 chr19 55385345 55403250 + MYCN chr2 15940550 15947007 + PELP1 chr17 4669774 4704337 - HSP90AA1 chr14 102080738 102139699 - GMPS chr3 155870650 155944020 + COPA chr1 160288594 160343273 - PLEKHO2 chr15 64841883 64868002 + MAP2K4 chr17 12020829 12143830 + LAPTM4B chr8 97775057 97853013 + RBX1 chr22 40951347 40973309 + C11orf24 chr11 68261338 68272001 - CRYL1 chr13 20403666 20525873 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022311.1 chr22 37876148 37895563 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.