exRNAdisease

Entry Detail

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General Information

Database ID: exR0755295 RNA Name: ABCD4 RNA Type: mRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 74285269 End Site(bp): 74303055 External Links: ENSG00000119688

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand QSER1 chr11 32892820 32993316 + MRPL46 chr15 88459477 88467390 - MXRA8 chr1 1352689 1361777 - NSUN2 chr5 6599239 6633291 - M6PR chr12 8940361 8949761 - SIK1 chr21 43414483 43427131 - RPL10 chrX 154389955 154409168 + SFI1 chr22 31488688 31618588 + C5orf24 chr5 134845680 134859735 + RDH13 chr19 55039108 55071291 - CRYL1 chr13 20403666 20525873 - LONRF3 chrX 118974614 119018355 + ORC3 chr6 87590067 87667453 + ACOT8 chr20 45841721 45857405 - TP53RK chr20 46684365 46689444 - ZNF668 chr16 31060843 31074240 - PFN1 chr17 4945652 4949061 - LTK chr15 41503637 41513887 - TOMM40L chr1 161225939 161230746 + FBXW4 chr10 101610664 101695295 - NEO1 chr15 73051710 73305205 + SELENOS chr15 101270817 101277500 - NHP2 chr5 178149460 178153967 - EIF4H chr7 74174245 74197101 + HSP90AB1 chr6 44246166 44253888 + BTBD2 chr19 1985438 2034881 - TRIP13 chr5 892884 919357 + HSPA4 chr5 133052013 133106449 + CCDC167 chr6 37482938 37499893 - VMP1 chr17 59707192 59842255 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005519.1 chr14 74289127 74294425 - AC005562.1 chr17 30576464 30672789 + AC007952.4 chr17 19112000 19112636 - AC011476.2 chr19 55027593 55053928 - MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.