exRNAdisease

Entry Detail

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General Information

Database ID: exR0755315 RNA Name: ABHD4 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 22598237 End Site(bp): 22613215 External Links: ENSG00000100439

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FAM219A chr9 34398184 34458570 - RPL32 chr3 12834485 12841582 - ZNF708 chr19 21291160 21329425 - AP2A1 chr19 49766968 49807113 + ARHGEF4 chr2 130836916 131047263 + POLD4 chr11 67350772 67356972 - PITPNC1 chr17 67377281 67697261 + TUBA1A chr12 49184795 49189080 - TRIP6 chr7 100867387 100873454 + AXIN1 chr16 287440 352723 - HAT1 chr2 171922448 171983686 + MYL12A chr18 3247481 3256236 + HNRNPA1 chr12 54280193 54287088 + PSMB8 chr6 32840717 32844679 - MT-CO1 chrMT 5904 7445 + GAPDH chr12 6534512 6538374 + CNPPD1 chr2 219171897 219178106 - DDX1 chr2 15591178 15631111 + HNRNPK chr9 83968083 83980616 - OGT chrX 71533104 71575892 + PUM1 chr1 30931506 31065991 - BTBD2 chr19 1985438 2034881 - PSAP chr10 71816298 71851325 - EWSR1 chr22 29268009 29300525 + EIF6 chr20 35278911 35284985 - KDM5B chr1 202724495 202808487 - CBSL chr21 6444869 6468040 - AL121753.1 chr20 35267885 35280043 - CCT8 chr21 29055805 29073797 - TRPV3 chr17 3510502 3557995 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-31-5p chr9 21512158 21512178 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AGAP1-IT1 chr2 235505751 235507566 + GATA2-AS1 chr3 128489212 128502970 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.