exRNAdisease

Entry Detail

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General Information

Database ID: exR0755320 RNA Name: ABI3 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 49210411 End Site(bp): 49223225 External Links: ENSG00000108798

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010422.3 chr19 12643831 12648397 - ANKRD46 chr8 100509752 100559784 - CDC37 chr19 10391133 10420121 - CFLAR chr2 201116154 201176687 + ETAA1 chr2 67397322 67412089 + GRK2 chr11 67266473 67286556 + HSPA8 chr11 123057489 123063230 - LMNB2 chr19 2427638 2456959 - MSN chrX 65588377 65741931 + MYL6B chr12 56152256 56159647 + PBK chr8 27809624 27838082 - PPP1R32 chr11 61481120 61490931 + PPP4C chr16 30075978 30085376 + PTDSS2 chr11 448268 491399 + RHOG chr11 3826978 3840959 - RPL8 chr8 144789765 144792587 - RPS8 chr1 44775251 44778779 + SKP1 chr5 134148935 134177038 - TMEM216 chr11 61392360 61398863 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.