exRNAdisease

Entry Detail

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General Information

Database ID: exR0755323 RNA Name: ABLIM1 RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 114431113 End Site(bp): 114768061 External Links: ENSG00000099204

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CDH1 chr16 68737292 68835541 + SMIM14 chr4 39546336 39638902 - SLC39A7 chr6 33200445 33204439 + COA6 chr1 234373456 234385068 + EEF2 chr19 3976056 3985463 - ZNF529 chr19 36534774 36605276 - PRRC2B chr9 131373636 131500197 + GAPDH chr12 6534512 6538374 + BTBD10 chr11 13388001 13463297 - EIF4B chr12 53006158 53042209 + MT-CO1 chrMT 5904 7445 + MT-ND1 chrMT 3307 4262 + CCNK chr14 99481169 99535044 + CRTAP chr3 33114014 33147773 + DDX47 chr12 12813316 12829981 + HSP90AA1 chr14 102080738 102139699 - MT-CO3 chrMT 9207 9990 + ACTR1A chr10 102461881 102502712 - HLA-B chr6 31269491 31357188 - EIF3E chr8 108201216 108435333 - BTG2 chr1 203305491 203309602 + RPS7 chr2 3575260 3580920 + P4HB chr17 81843161 81860624 - GNAI3 chr1 109548615 109600195 + TRIR chr19 12730640 12734684 - ANAPC11 chr17 81890790 81900991 + WBP11 chr12 14784582 14803486 - MRPS7 chr17 75261674 75266376 + ALAS1 chr3 52198086 52214327 + ZNF189 chr9 101398873 101410660 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3136-3p chr3 69048966 69048987 - hsa-miR-7111-3p chr6 35470558 35470579 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand MAPKAPK5-AS1 chr12 111839764 111842902 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.